Cabolong 20mg

Product Description

Cobolong 20 mg tablet is a medication used in the treatment of liver, kidney, and thyroid cancer. Cobolong 20 mg contains Cabozantinib belongs to a class of drugs called tyrosine kinase inhibitors (TKIs), which target tyrosine kinases (enzymes) involved in the growth and spread of cancer cells.

How Cabolong 20mg Works

Cabolong 20 mg tablet targets proteins in the body called tyrosine kinases. These proteins play a role in cell growth, survival, and movement in cancer cells. By inhibiting these proteins, cabolong 20mg can slow down or stop the growth of cancer cells and prevent the formation of new blood vessels that cancer tumors need to grow.

Uses of Cabolong 20mg

Cabolong 20mg is used to treat several types of cancer:

1. Renal Cell Carcinoma (RCC): For advanced kidney cancer, especially in patients who have tried other treatments without success.
2. Hepatocellular Carcinoma (HCC): For liver cancer in patients who have previously been treated with another drug called sorafenib.
3. Medullary Thyroid Cancer (MTC): For patients with a type of thyroid cancer that has spread or is growing.

Dosage and How to Take It

The dosage of Cabolong can vary depending on the type of cancer being treated and how the patient responds to the medication.

• For RCC and HCC: The typical starting dose is 60mg once daily. If side effects occur, the dose may be reduced to 40mg or 20mg once daily.
• For MTC: The starting dose is usually 140mg once daily, but this may be adjusted based on patient tolerance.

Cabozantinib should be taken on an empty stomach, at least one hour before or two hours after eating. Swallow the tablets whole without crushing or chewing them.

Potential Side Effects of Cabolong 20mg

Like all medications, Cabolong 20 mg can cause side effects. Common side effects include:

• Diarrhea
• Fatigue
• Decreased appetite
• Weight loss
• Nausea and vomiting
• High blood pressure
• Hand-foot syndrome (Redness, swelling, and pain on the palms of the hands or soles of the feet)

Some serious side effects that require immediate medical attention include:

• Severe bleeding
• Holes or tears in the stomach or intestines
• Problems with wound healing
• Liver problems
• High blood pressure

Drug Interactions

Cabolong 20mg tablet can interact with other medications, which might change how it works or increase the risk of serious side effects. Important interactions include:

• CYP3A4 Inhibitors and Inducers: Drugs that affect the enzyme CYP3A4 can change the levels of Cabolong 20mg in the body. For example, certain antifungal drugs (like ketoconazole) can increase Cabozantinib levels, while drugs used to treat seizures (like phenytoin) can decrease its levels.
• Anticoagulants and Antiplatelet Agents: Taking these with Cabozantinib can increase the risk of bleeding.
• Other TKIs: Using multiple tyrosine kinase inhibitors together can increase the risk of side effects.

Always tell your doctor about all the medications and supplements you are taking to avoid potential interactions.

Precautions and Warnings

There are several important precautions to be aware of when taking Cabolong 20mg:

• Pregnancy and Breastfeeding: Cabozantinib can harm an unborn baby. Women who could become pregnant should use effective contraception during treatment and for at least four months after the last dose. Breastfeeding is not recommended during treatment and for four months after stopping the medication.
• Wound Healing: Cabozantinib can affect how your body heals. If you need surgery, you should stop taking the medication at least 28 days before the procedure and not resume until your doctor says it is safe.
• High Blood Pressure: Cabozantinib can cause or worsen high blood pressure. Regular monitoring is necessary.
• Liver Function: Regular blood tests are needed to monitor liver function, as Cabozantinib can cause liver problems.

Patient Experience and Effectiveness

Clinical trials have shown that Cabolong 20mg tablet can extend the time it takes for certain cancers to progress and can improve survival rates in some patients. For example, in kidney cancer, studies have shown that Cabozantinib can significantly slow down disease progression compared to other treatments.

Patients often report that Cabozantinib helps manage symptoms and improve their quality of life. However, the experience of side effects can vary widely, and managing these is important for maintaining a good quality of life during treatment.

Conclusion

Cabolong 20 mg tablet is an important medication for treating advanced cancers, including kidney, liver, and thyroid cancers. By targeting specific proteins that contribute to cancer growth, Cabozantinib can help slow down the progression of these diseases. Understanding how to take the medication, being aware of potential side effects and drug interactions, and following precautions can help ensure the best possible outcomes. Always consult with your healthcare provider for personalized advice and to make sure Cabozantinib is the right treatment for your specific situation.

Additional information